c l i n i c a l f o l i o s : n a r r a t i v e





A D V E R T I S E M E N T

 

Sarcoma of the Knee: 13

A D V E R T I S E M E N T

   
 

The gross appearance of the tumor embedded in a wide margin of fat, with the attached needle tract is shown.       

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Sarcoma of the Knee: 14

A D V E R T I S E M E N T

   
 

The cut surface shows a white fibrous rim with central necrosis.       

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Sarcoma of the Knee: 15

A D V E R T I S E M E N T

   
 

The tumor showed lobular architecture, areas of spindled and epitheliod malignant cells, and focal rosette formation. There were large areas of necrosis and dystrophic calcification. There was brisk mitotic activity. Immunoperoxidase stain was positive for MSE and negative for pan-cytokeratin, cytokeratin 7, desmin, EMA, S-100, synaptophysin and glycogen. Differential diagnosis includes primitive neuroectodermal tumor (malignant peripheral neuroepithelioma) and synovial sarcoma. Further review and reverse transcriptase PCR analysis for t(11;22) and t(X;18) translocations were pending.     

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This page was last modified on 6/16/2001.